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Platform

The RevMod Platform

Our proprietary RevMod Platform uses a modular plug-and-play system to streamline and accelerate the efficient drug discovery and development of multispecific biologics across a broad range of diseases.

The MultiMod

This customizable multispecific biologic is built from highly compatible modular subunits to provide innovative solutions to complex diseases.1

The True Human
MultiMod

It's also enabled by a naturally occurring, fully human, universal light chain that supports the integration of diverse binding domains.1

The RevMod Platform can be used to rapidly and
effectively create multispecific biologics.

BiMod Biologics

Can be used to target 2 distinct
disease pathways.

TriMod Biologics

Can be used to target 3 distinct disease pathways. Our first-in-class candidate,
RO-104, is a TriMod biologic designed to treat retinal vascular disease.

TetraMod Biologics and Beyond

Can be used to singularly target 4+ distinct disease pathways.

Our proprietary platform boasts a vast library of nearly 30 billion fully human antibody components in a structured phage display system, facilitating rapid identification and assembly of multispecific product candidates. With seamless compatibility, the RevMod platform enables swift and efficient design of multispecific biologics to address unmet needs in major therapeutic areas including ophthalmology, oncology, and immune-mediated diseases.1

RevMod

Benefits of the RevMod Platform1

One molecule, multiple targets:

  • Native, non-engineered biologics
  • Elegant modular solutions
  • Targets multiple disease pathways

Fully human:

  • Fully human antibody sequences and architecture
  • Maximizing efficacy and drug-like properties
  • Well tolerated by the human body

Derived from nature:

  • Light chain based on the surrogate light chain
  • Naturally occurring precursor formed in all humans
  • Universal natural partner for all human heavy chain binding domains

Rapid discovery and development:

  • Platform supports efficient screening
  • Customizable plug-and-play design of molecules
  • Optimal solutions to complex diseases

How can the RevMod Platform be leveraged
to treat other diseases?

Learn more

Reference: 1. Xu L, et al. Proc Natl Acad Sci USA. 2008;105(31):10756-10761.